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IRSST - Institut de recherche Robert-Sauvé en santé et en sécurité du travail
OHS Research
Research at the IRSST
Reference Framework
Scientists Directory
Publications and Tools
IRSST's Production
Magazine and Newsletter
Scientific Watch
Documentation Center
Useful Links
Laboratory Services
Laboratories
Analysis and Testing Services
Laboratory Methods
Masks Efficacy Evaluation
Workplace Air Contaminants
Slip Resistance Test for Protective Footwear
Loan, Calibration and Repairs
Recognition Programs
CQ Fibres
Quality Control of Fiber Counts
CQ Vrac
Recognized Laboratories
Interlaboratory quality
control program
Guides and Tools
Instruments and Sampling Material
Register
Research Fund and Partnerships
Research Fund and Partnerships
Grants
Scholarships
Master’s Scholarship and Supplement
Doctoral Scholarship and Supplement
Postdoctoral Fellowship
Research partnerships
Institute
About
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substance
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substance
August 30, 2025
Warfarin (Pi)
French name in the regulation:
Warfarin (Pi)
CAS :
81-81-2
Synonyms:
Warfarine
Exposure Standards in RROHS regulation
Permissible exposure values (PEV)
ppm
mg/m
3
f/cc
Notes
TWAEV
-
0,01
-
Pi
STEV
-
-
-
-
Ceiling
-
-
-
-
Carcinogenicity
Sensitizer
Simple asphyxiant
Percutaneous
Prohibited use
Prohibited recirculation
Minimum exposure
Explosion hazard
Ototoxic
TWA adjustment for unusual work schedules
IV
: Daily or weekly adjustment ( the more stringent of the two)
CNESST – Toxicological Index Service
Consult REPTOX file:
Warfarin(Pi)
Analysis:
Warfarin
Recommended method by the IRSST:
Method: NIOSH - 5002
Sampling protocol
Sampling device:
Polytetrafluoroethylene (teflon) filter
Parameters:
Flow rate: 1-4 L/min
TWA sampling volume: 400 L
STEL sampling volume: -
Remarks:
The aerosol phase might be underestimated because the efficiency of the sampling device does not match inhalable fraction definition. This substance is not analyzed by our laboratories. It might be possible that the analysis is performed by another laboratory. Please contact the IRSST before sampling.
Analytical protocol
Principle:
High performance liquid chromatography with UV detection (HPLC-UV)
Remarks:
The recommended method allows analysis of the substance but is not sensitive enough for an adequate comparison to the permissible exposure value.
Reference
NIOSH Manual of Analytical Methods, 4th ed., Method 5002: Warfarin, 1994.
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