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IRSST - Institut de recherche Robert-Sauvé en santé et en sécurité du travail
OHS Research
Research at the IRSST
Reference Framework
Scientists Directory
Publications and Tools
IRSST's Production
Magazine and Newsletter
Scientific Watch
Documentation Center
Useful Links
Laboratory Services
Laboratories
Analysis and Testing Services
Laboratory Methods
Masks Efficacy Evaluation
Workplace Air Contaminants
Slip Resistance Test for Protective Footwear
Loan, Calibration and Repairs
Recognition Programs
CQ Fibres
Quality Control of Fiber Counts
CQ Vrac
Recognized Laboratories
Interlaboratory quality
control program
Guides and Tools
Instruments and Sampling Material
Register
Research Fund and Partnerships
Research Fund and Partnerships
Grants
Scholarships
Master’s Scholarship and Supplement
Doctoral Scholarship and Supplement
Postdoctoral Fellowship
Research partnerships
Institute
About
Activity Report
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Policies
Research Ethics Committee
Strategic Plan
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substance
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substance
August 27, 2025
Dimethyl sulfate
French name in the regulation:
Sulfate de diméthyle
CAS :
77-78-1
Synonyms:
Sulfate de méthyle; Sulfate diméthylique
Exposure Standards in RROHS regulation
Permissible exposure values (PEV)
ppm
mg/m
3
f/cc
Notes
TWAEV
0,1
0,52
-
-
STEV
-
-
-
-
Ceiling
-
-
-
-
Carcinogenicity
C2
Sensitizer
Simple asphyxiant
Percutaneous
Prohibited use
Prohibited recirculation
Minimum exposure
Explosion hazard
Ototoxic
TWA adjustment for unusual work schedules
III
: Weekly adjustment
CNESST – Toxicological Index Service
Consult REPTOX file:
Dimethyl sulfate
Analysis:
Sulfate de diméthyle
Recommended method by the IRSST:
Method: NIOSH - 2524
Sampling protocol
Sampling device:
Porapak tube
Parameters:
Flow rate: 0,01-0,2 L/min
TWA sampling volume: 6 L
STEL sampling volume: -
Remarks:
This substance is not analyzed by our laboratories. It might be possible that the analysis be performed by another laboratory. Please contact the IRSST before sampling.
Analytical protocol
Principle:
Gas chromatography with electrolytical conductivity detection (GC-ELD)
Reference
NIOSH Manual of Analytical Methods, 4th ed., Method 2524 : Dimethyl Sulfate, 1994.
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