Experimental asbestosis: early radiographic signs of pulmonary pathology Abstract Early detection of asbestosis is difficult. This study was undertaken, in conjunction with other research, to identify the initial radiographic signs of the disease. The experimental approach used involved controlled exposure of the animal model to dust, followed by sequential analysis of lung x-rays. This analysis showed a decrease in the radiographic clarity of pulmonary circulation, along with the appearance of histological and functional modifications. The study confirmed the importance of serial x-rays in observing the initial stages of asbestosis. The pertinence of the experimental model having already been demonstrated, further research on the early detection of the disease in humans appears promising. Produced Under this Project Scientific Publications Asbestos-induced lung injury in the sheep model : The initial alveolitisBégin R., Rola-Pleszczynski M., Massé S., Lemaire I., Sirois P., Boctor M., Nadeau D., Drapeau G., Bureau M. A.Source : Environmental Research, vol. 30, no 1, 1983, p. 195- 210Pathological, radiological and functional correlations in early asbestosis of the sheepMassé S., Boctor M., Bégin R.Source : in ILO (International Labour Organisation) International Pneumoconiosis Conference, (6e : 1984), ILO (International Labour Organisation) VIth International Pneumoconiosis Conference, vol. 2, 1984, p. 961-987 Additional Information Type: Project Number: 0079-0040 Status: Completed Year of completion: 1982 Research Field: Chemical and Biological Hazard Prevention Team: Raymond Bégin (Université de Sherbrooke)Serge Massé (Université de Sherbrooke)Marek Rola-Pleszczynski (Université de Sherbrooke)Pierre Sirois (Université de Sherbrooke)