IRSST - Institut de recherche Robert-Sauvé en santé et en sécurité du travail

Experimental asbestosis: early radiographic signs of pulmonary pathology

Abstract

Early detection of asbestosis is difficult. This study was undertaken, in conjunction with other research, to identify the initial radiographic signs of the disease. The experimental approach used involved controlled exposure of the animal model to dust, followed by sequential analysis of lung x-rays. This analysis showed a decrease in the radiographic clarity of pulmonary circulation, along with the appearance of histological and functional modifications. The study confirmed the importance of serial x-rays in observing the initial stages of asbestosis. The pertinence of the experimental model having already been demonstrated, further research on the early detection of the disease in humans appears promising.

Additional Information

Type: Project
Number: 0079-0040
Status: Completed
Year of completion: 1982
Team:
  • Raymond Bégin (Université de Sherbrooke)
  • Serge Massé (Université de Sherbrooke)
  • Marek Rola-Pleszczynski (Université de Sherbrooke)
  • Pierre Sirois (Université de Sherbrooke)