Beryllium - Preliminary Agenda

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Tuesday , March 8, 2005
7:00 - 8:00 A.M.	Registration and Continental Breakfast
8:00 - 8:05	Welcome Diane Gaudet, President CEO, Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST)
8:05	Meeting Overview Chantal Dion, PhD, IRSST, Chair of the scientific committee
SESSION 1 Overview of Beryllium Uses, Health Effects, Exposure, and Surveillance
8:15	Beryllium Properties and Uses Mark D. Hoover, PhD, CHP, CIH, National Institute for Occupational Safety and Health (NIOSH)
8:45	History of Beryllium Disease Milton Rossman, MD, University of Pennsylvania Medical Center
9:15	Diagnosis and Management of Beryllium Sensitization and CBD Raed Dweik, MD, Cleveland Clinic Foundation
10:00 - 10:15	Break
10:15	Epidemiology of Beryllium Sensitization and CBD Peggy Mroz, MSPH , National Jewish Medical and Research Center (NJC)
10:45	Measurement and Prevention of Beryllium Exposure in Facilities with Beryllium Sylvain Laparé, PhD, Noranda Inc./Falconbridge Ltd John Martyny, PhD, CIH, National Jewish Medical and Research Center (NJC)
11:45 - 1:00 P.M.	Group Luncheon
1:00	Process and Exposure-Related Risk for Beryllium Sensitization and CBD Paul Henneberger, MPH, ScD, National Institute for Occupational Safety and Health (NIOSH)
1:45	Teaching Points from Current Clinical Cases (Panel) Panel moderator: Lee Newman, MD, MA, National Jewish Medical and Research Center (NJC) Milton Rossman, MD, Hospital of the University of Pennsylvania Raed Dweik, MD, FACP, FCCP, FRCP(C), The Cleaveland Clinic Foundation Lisa Maier, MD, MSPH, National Jewish Medical and Research Center (NJC) Gaston Ostiguy, MD, M.Sc, FRCP (C), McGill University Health Center, Montréal Chest Institute Suzan Tarlo, MB,BS, FRCP (C), University of Toronto
3:00 - 3:15	Break

SESSION 2 Examples of Medical Surveillance Programs
3:15	National Institute for Occupational Safety and Health Beryllium Research Program Christine Schuler, PhD, National Institute for Occupational Safety and Health (NIOSH)
3:55	Medical Surveillance in the Recycling Industry Jean-Paul Robin, MD, Noranda Inc./Falconbridge Ltd
4:35	Beryllium Health Surveillance in U.S. Department of Energy Facilities Arthur W. Stange, PhD, Oak Ridge Institute for Science and Technology (ORISE)
5:15	Adjournment

5:30 - 7:00 P.M.	Reception and evening proceedings (Room Le Portage)
	Welcoming Addresses and Perspectives on Occupational Disease with Chronic Beryllium Disease as an Example Ms Diane Gaudet, President CEO, Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST) Dr Kathleen Kreiss, Field Studies Branch Chief, Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health (NIOSH) Dr Lee Newman, Professor and Head, Divison of Environmental and Occupational Health Sciences, National Jewish Medical and Research Center (NJC)

Wednesday, March 9, 2005
7:00 - 8:00 A.M.	Continental Breakfast
SESSION 3 International Overview of Beryllium Disease and Exposure Assessment
8:00	Scope of the Problem: Industrial Dissemination of Beryllium and Disease Keynote speaker: Lee Newman, MD, MA, National Jewish Medical and Research Center (NJC)
8:45	Problematic beryllium: current situation in Québec Louis Tremblay, Commission de la santé et de la sécurité du travail (CSST)
9:15	Occupational Exposure to Beryllium in France Raymond Vincent, INRS
9:45 - 10:00	Break and viewing of posters
10:00	The Search for Berylliosis in Israel: First Five Years (1999-2004) Élizabeth Fireman, PhD, Tel-Aviv Medical Center
10:30	Overview of Beryllium Control and its Exposure Assessment : An Update D.D. Thorat, Bhabha Atomic Research Centre, India
11:00	Diagnoses of Chronic Beryllium Disease within Cohorts of Sarcoidosis Patients Joachim Müller-Quernheim, MD, Medical University of Freiburg
11:30	Making 'sense' and 'non sense' of international research on beryllium toxicity Andrew Watterson, PhD, FIOSH, RSP, University of Stirling
12:00	Beryllium Health and Safety Committee Kathryn Creek, Los Alamos National Laboratory (LANL)
12:30 - 1:30	Group Luncheon
SESSION 4 Industrial Hygiene Update
1:30	Critical Gaps and Needed Industrial Hygiene Actions to Understand and Prevent Beryllium Sensitization and CBD Keynote speaker: Mark D. Hoover, PhD, CHP, CIH, National Institute for Occupational Safety and Health (NIOSH)
2:00	Characterization of Beryllium Aerosols Aleksandr B. Stefaniak, PhD, National Institute for Occupational Safety and Health (NIOSH)
2:25	Skin as a Route of Exposure to Beryllium Gregory A. Day, PhD, National Institute for Occupational Safety and Health (NIOSH)
2:50	Use of Leading Measures to Prevent CBD in the Beryllium Supply Chain Michael Kent, MS, CIH, Brush Wellman Inc.
3:15	Break and viewing of posters
3:30	Approaches to Control of Beryllium in Production and D&D Workplace Activities Robert Bistline, PhD, United States Department of Energy (U.S. DOE)
3:55	What is a "safe" level of exposure for return to work? John Martyny, PhD, CIH, National Jewish Medical and Research Center (NJC)
4:20	Setting Administrative Guidelines and Standards Arthur W. Stange, PhD, Oak Ridge Institute for Science and Technology (ORISE)
4:45	General Discussion
5:00	Adjournment


Thursday, March 10, 2005
7:00 - 8:00 A.M.	Continental Breakfast
SESSION 5 Molecular, and Genetic Mechanisms of Chronic Beryllium Disease and Beryllium Sensitization
8:00	Update on Beryllium Genetics, and Immunology Keynote speaker: Lisa Maier, MD, MSPH, National Jewish Medical and Research Center (NJC)
8:45	Beryllium-Ferritin Induced Macrophage Apoptosis Dick Sawyer, PhD, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH)
9:15	Beryllium T cell-MHC Interactions Massimo Amicosante, MD, University of Rome
9:45	Break and viewing of posters
10:00	Molecular Modeling and Molecular Epidemiology Investigations of Chronic Beryllium Disease Ainsley Weston, PhD, National Institute for Occupational Safety and Health (NIOSH)
10:30	Beryllium and Oxidative Stress Dick Sawyer, PhD, National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health (NIH)
11:00	General Discussion
11:30 - 12:45 P.M.	Group Luncheon
SESSION 6 New Approaches to Medical Surveillance Testing
12:45	Perspectives on Medical Surveillance Testing Keynote speaker: Kay Kreiss, MD, National Institute for Occupational Safety and Health (NIOSH)
1:30	Beryllium Lymphocyte Proliferation Testing Donna Cragle, PhD, Oak Ridge Institute for Science and Technology (ORISE)
2:00	Alternative Lymphocyte Proliferation Tests: BrdU and Flow Cytometry Based Tests Tim Takaro, MD, MPH, University of Washington
2:30	Break and viewing of posters
2:45	Neopterin Testing as a Potential Diagnostic Tool in CBD Peggy Mroz, MSPH, National Jewish Medical and Research Center (NJC)
3:15	ELISPOT, Implications for Molecular Mechanisms and Diagnosis Andrew Fontenot, MD, University of Colorado Health Sciences Center (UCHSC)
4:00 - 5:30	POSTER SESSION AND DISCUSSION WITH THE AUTHORS Place: St-Léonard and Longueuil rooms


Friday, March 11, 2005
7:00 - 8:00 A.M.	Continental Breakfast
SESSION 7 Risk Communication
8:00-9:00 A.M.	Training - Effective Tool for Practical Application of the Newest Data on Beryllium through Risk Communication and Involvement of Interested Stakeholders (Panel)
	Panel moderator: Maria Pavlova, MD, PhD, United States Department of Energy (U.S. DOE) Tim Takaro, MD, MPH, University of Washington Bob Immele, Pacific Northwest National Laboratories Robert Bistline, PhD, United States Department of Energy (U.S. DOE)
SESSION 8 Abstracts presentation
9:00	Beryllium Exposure and Disease Among Construction Workers Laura S. Welch, J. Dement, K. Ringen, P. Susi, T. Peterson
9:20	Identification of Beryllium Exposure in some Primary Metal Industries and Aeronautics Plants Operating a Foundry: the Québec Experience France Labrèche, J. Forest, C. Lafortune
9:40	Occupational Beryllium Exposure in Primary Aluminium Production Yngvar Thomassen, D.G. Ellingsen, K. Dahl, I. Martinsen, N.P. Skaugset, P.A. Drabløs
10:00	The Reliability of the Beryllium Lymphocyte Proliferation Test (BeLPT): The "Québécoise" Experience Pauline Brousseau, M. Rossignol, B. Mazer, C. Dion
10:20	Break
10:40	Exploring Determinant Factors for Beryllium Exposure Assessment in Occupational Settings Chantal Dion, A. Dufresne, Y. Cloutier, G. Perrault, S. Viau
11:00	Exposure Risk Factors Associated with Beryllium Sensitivity in Former Workers at the Nevada Test Site (NTS) Ema Rodrigues, L. Pepper, M. McClean, H. Keith-Lucas, L. Haskell, R. Harrison, J. Guerriero, R. Meister.
11:20	Bronchoalveolar Lavage Heterogeneity in Chronic Beryllium Disease Tristan Barnes, M. Gillespie, L. Silveira, L. Maier, L. Newman
11:40 - 12:10 P.M.	Sessions Summary and Further Research Needs
12:10	Symposium Summary
12:20	Conference closing

Wednesday and Thursday

POSTER SESSION
(Authors will be on-site to answer questions on Thursday, March 10th between 4 p.m. and 5:30 p.m.)

St-Léonard Room
Competitive Metal Binding by Displacement Isothermal Titration Calorimetry: A Study of Be2+-Ca2+-EDTA
Chadi H. Stephan, M. Lafleur, M. Fournier, S. Sauvé

Physical and chemical characterization of beryllium particles from several workplaces in Québec (Canada) –Time-of-flight secondary ion mass spectroscopy
Joseph Zayed, M. Rouleau, C. Dion, P. Plamondon, G. L'espérance, G. Kennedy

Challenges of a Chronic Beryllium Disease Patient
Bob Immele

Hanford Beryllium Awareness Group (BAG)
Tom Peterson, T.C. Ledford

Worker Implementation of Brush Wellman's CBD Prevention Model-Case Study
Dan Draper, T. Noblit

Beryllium Handling Experience at the JET Fusion Research Facility and Future Prospects in Fusion Research
Bharat Patel, D. Campling, P. Macheta

Ethical stakes in screening workers exposed to beryllium: usefulness of a risk management framework
Maurice Poulin

Longueuil Room Technical Observations and Discussions on the Uses of a Micro-Orifice Uniform Deposit Impactor (Moudi) Model 110 Rotatin in Beryllium Exposure Assessment
Cloutier,Yves, C. Dion, A. Dufresne, G. Perrault, R. Gravel, S. Viau

Beryllium exposure in foundries and aeronautics industries in Montréal, Québec
Jocelyne Forest, F. Labrèche

Effects of Beryllium on Natural Immunity
Anne Larrivée, M. Fournier, R. Mandeville, P. Brousseau

Reduced Beryllium Exposure and Disease at a Precision Machining Facility
Holly M. Sackett, M.V. VanDyke, M.M. Mroz. J.W. Martyny, L. Newman

Symptoms among Workers Diagnosed with a Beryllium Related Disease in Québec, 1999-2002
Louise De Guire, F. Labrèche, S. Provencher, M. Guimond, G. Ostiguy

Comparison of Systematic Exposure Assessment to Daily Air Monitorring at a Beryllium Machining Facility
Michael V. Van Dyke, J.W. Martyny, M.M. Mroz, H.M. Sackett, L.A. Maier, L. Newman

Exposure Assessment Methods Used for Risk Assessment in a Beryllium Alloy Strip and Wire Finishing Facility
André Dufresne, M. Kent, G. Day, D. Deubner