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Project IRSST
 | Occupational exposures and reproductive functions of males: state of knowledgeLarissa Takser,
Guylain Boissonneault
/ Université de Sherbrooke
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0099-8740 : Ongoing
Numerous studies report a slight reduction in fertility in men in the last century, and several reasons have been given. An exploratory study carried out in Estrie, linking occupational exposures and infertility problems in CHUS fertility clinic patients has established a link between these problems and work in the manufacturing sector. There is therefore a reason for further exploration of this research avenue.
The objective of this study is to carry out a systematic and critical review of existing scientific studies on the relationship between occupational exposures to regulated contaminants in Québec and male fertility. This literature review will allow the relevance of studying this issue to be evaluated and the research orientations to be defined.
Scientific publications and communicationsActeau G.,
Carrier-Leclerc A.,
Leduc F.,
Simard O.,
Arguin M.,
Boissonneault G.
Identification of the DNA damage response pathway to endogenous strand breaks in spermatids as a new male-driven source of genetic instability
in Symposium du Réseau québécois en reproduction / RQR (3e : 16-17 novembre, 2010 : Québec, Canada), 2010.
Bikond Nkoma G.,
Leduc F.,
Jouad L.,
Boissonneault G.
Electron microscopy analysis of histone acetylation and DNA strand breaks in mouse elongating spermatids using a dual labelling approach
Andrologia, vol. 42, no 5, 2010, p. 322-325.
Carrier-Leclerc A.,
Acteau G.,
Leduc F.,
Arguin A.,
Boissonneault G.
The DNA repair pathway in spermatids, a possible cause of male infertility
in Innovations in Gender, Sex, and Health Research Conference (November 21-22, 2010 : Toronto, Canada), 2010.
Grégoire M.-C.,
Leduc F.,
Boissonneault G.
Spermiogenesis in Sperm Genetic Integrity
in Sperm chromatin: biological and clinical application in male infertility and assisted reproduction, Zini, A.; Argawa, A. (éds), Springer, 2011, chapter 21.
Johnson G. D.,
Lalancette C.,
Linnemann A. K.,
Leduc F.,
Boisonneault G.,
Krawetz S. A.
The sperm nucleus: chromatin, RNA, and the nuclear matrix
Reproduction, vol. 141, no 1 , 2011, p. 21-36.
Leroux J.,
Arguin M.,
Acteau G.,
Boissonneault G.
Epigenetic contribution to the genetic instability of haploid male germ cells
in Innovations in Gender, Sex, and Health Research Conference (November 21-22, 2010 : Toronto, Canada), 2010.
Leroux J.,
Arguin M.,
Acteau G.,
Boissonneault G.
Epidenetic contribution to the genetic instability of haploid male germ cells
in Symposium du Réseau québécois en reproduction / RQR (3e : 16-17 novembre, 2010 : Québec, Canada), 2010.
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